ABSTRACT
Large hyperplastic polyps of the duodenum are very rare. We report the case of a 61-year-old women with a large lobulated and pedunculated hyperplastic polyp in the distal second portion of the duodenum causing anemia which was treated with snare polypectomy. Endoscopy revealed a 2.5 cm sized lobulated and pedunculated polyp with a long stalk in the distal second portion of duodenum. Previous studies reported that duodenal polyps larger than 10 mm in diameter or polyps in the second portion as independent risk factors of neoplastic lesions, and thus an accurate pathologic examination was needed. Many patients with large duodenal hyperplastic polyps present with gastrointestinal bleeding and anemia. We removed the duodenal polyp by a snare with electrocautery after clipping and epinephrine injection into the stalk to prevent bleeding. Histopathological examination of the polyp revealed hyperplasia.